Synthesis of 2-Substituted Benzo[b]furans/furo-Pyridines Catalyzed by NiCl2
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چکیده
منابع مشابه
An Efficient Synthesis of Arylated Pyridines from Conjugated Acetylenes and Substituted Benzylamines Catalyzed by Base.
An efficient base-catalyzed synthesis of arylated pyridines has been disclosed. This reaction involving conjugated acetylenes and substituted benzylamines proceeded smoothly, giving rise to tri-aryl substituted pyridines which are biologically relevant compounds in good to excellent yields in N,N-dimethylformamide (DMF) under air at 140 °C with K₂CO₃ as catalyst.
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The novel palladium-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid with aryl and heteroaryl bromides including benzenes, naphthalenes, pyridines and quinolines for C-C bond formation have been successfully achieved.
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SYNTHESIS 2011, No. 20, pp 3209–3219xx.xx.2011 Advanced online publication: 07.09.2011 DOI: 10.1055/s-0030-1260212; Art ID: E69311SS © Georg Thieme Verlag Stuttgart · New York Abstract: The direct functionalization of pyridine and related azine derivatives through carbon–carbon bond-forming reactions is reviewed. Various transformations that use a variety of transitionmetal catalysts are covere...
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An effective regioselective cyclotrimerization of terminal alkynes is achieved by the direct utilization of NiCl2·6H2O, Zn, and 2-(benzimidazolyl)-6-(1-(arylimino)ethyl)pyridine in one step under ambient temperature.
متن کاملSynthesis and pharmacological activities of 2-(3'-substituted-2'-hydroxypropylamino)pyridines.
In the present study, a series of 2-(3'-substituted-2'-hydroxypropylamino)pyridines were synthesized and characterized by IR, 1H-NMR and elemental analysis. The compounds were investigated for anticonvulsant (150, 300 mg/kg) and cardiac activity. 2-(3'-Diethylamino-2'-hydroxypropylamino)pyridine 3 was found to exhibit the highest anticonvulsant activity. 2-(3'-Dimethylamino-2'-hydroxypropylamin...
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ژورنال
عنوان ژورنال: Catalysts
سال: 2019
ISSN: 2073-4344
DOI: 10.3390/catal9121019